Spoiled Francis (Mark Holton) covets his neighbor Pee-wee's (Paul Reubens) throwback red bicycle. Unwilling to sell, Pee-wee has his bike stolen out from under him, which triggers a road trip to get his bike back. With pit stops at the Alamo and biker bars, Pee-wee's big adventure takes him to various and memorable spots before he ultimately heads into the movies.