Andrew Mesecar, Walther Professor in Cancer Structural Biology, Purdue University.
Coronaviruses are all around us and they infect humans and animals alike. In their most deadly forms, they cause disease in humans such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). In animals, Porcine Epidemic Diarrhea virus (PEDV) killed millions of pigs in Indiana and the US in 2014, and 5% of household cats die from Feline Infectious Peritonitis Virus (FIPV) each year. This talk will focus on structure-based design strategies to develop selective and broad-spectrum coronavirus therapeutics.
Hosted by the (CBBI) Chemistry, Biochemistry, Biology Interface Program.